An analysis of data concerning more than a half million adults revealed that regular laxative use increases the risk for dementia over the following decade by 28% and regular use of two or more laxatives boosts the risk up to 90%. Study author Dr. Feng Sha adds, “Regular use of laxatives, even without short-term severe adverse events, may have the potential long-term risk of dementia, especially when it comes to osmotic laxatives and combination use of two or more types of laxatives.” Neurology, February 2023