A recent literature review found that for coronary heart disease patients with co-occurring depression, exercise may be a more effective tool for managing depression than antidepressants, psychotherapy, combined psychotherapy and antidepressants, and collaborative care. Study author Dr. Frank Doyle explains, “Our findings further highlight the clinical importance of exercise as a treatment as we see that it improves not only depression, but also other important aspects of heart disease, such as lowering blood pressure and cholesterol, in these patients.” Psychosomatic Medicine, June 2021